SS31

SS-31 (Elamipretide) – Premium Mitochondrial-Targeted Tetrapeptide for Cellular Energy & Anti-Aging Research | Protect Mitochondria, Boost ATP Production & Combat Oxidative Stress

Revolutionize your cellular health research with SS-31 (Elamipretide), the high-purity, mitochondria-penetrating tetrapeptide designed for advanced studies into mitochondrial dysfunction, oxidative stress reduction, and energy metabolism optimization. This innovative research compound selectively binds to cardiolipin on the inner mitochondrial membrane, stabilizing electron transport chain supercomplexes, enhancing ATP synthesis, and lowering reactive oxygen species (ROS) production — making it a leading tool for laboratories exploring age-related decline, cardiac protection, renal function, muscle performance, and neuroprotective pathways.

Premium Product Overview

SS-31, also known as Elamipretide or Bendavia (and formerly MTP-131), is a synthetic, water-soluble tetrapeptide with the sequence D-Arg-2′,6′-dimethylTyr-Lys-Phe-NH₂. It is typically supplied as a stable lyophilized powder in vials (commonly 10mg or higher) for easy reconstitution in research settings.

With a molecular formula of C₃₂H₄₉N₉O₅ and molecular weight of approximately 639.8 Da, SS-31 rapidly accumulates in mitochondria due to its cationic and aromatic properties. It binds with high affinity to cardiolipin, preventing peroxidation, inhibiting cytochrome c peroxidase activity, and optimizing oxidative phosphorylation. Produced at ≥99% purity (HPLC verified), this research-grade peptide offers exceptional bioavailability and mitochondrial selectivity for precise experimental investigations.

Key Research Benefits of SS-31 (Elamipretide)

• Mitochondrial Protection & Energy Boost: Stabilizes cardiolipin, improves electron transfer, increases ATP production, and reduces ROS by 30–50% in stressed cells — ideal for modeling enhanced cellular energetics and fatigue resistance.
• Cardiac & Muscle Support: Enhances cardiac function, stroke volume, and exercise tolerance in models of heart failure, Barth syndrome, and cardiomyopathy while supporting skeletal muscle recovery and strength.
• Renal & Neuroprotective Insights: Improves glomerular architecture, reduces senescence, and promotes cognitive and synaptic health in aging or injury models.
• Anti-Aging & Anti-Inflammatory Effects: Mitigates oxidative damage, supports tissue repair, and may preserve muscle mass during cachexia or metabolic stress, offering broad potential for longevity and performance research.

Researchers often call SS-31 the ultimate “mitochondrial guardian” or “energy repair peptide” for its targeted ability to restore mitochondrial health at the source.

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Quality Assurance & Usage in Research

Sourced exclusively for laboratory research, SS-31 reconstitutes easily with bacteriostatic water due to its excellent water solubility. Its small size and design ensure rapid mitochondrial uptake and stability when stored properly (lyophilized at -20°C, reconstituted refrigerated).

Common Research Protocols (for reference only): Subcutaneous administration in studied models often ranges from 2–10 mg/kg daily or 5–40 mg daily in human-equivalent protocols, with titration starting low. Some studies use 2–4 weeks of daily dosing or intermittent regimens (e.g., 2x weekly at 5 mg). Always follow precise reconstitution, dosing calculations, and institutional guidelines for optimal experimental efficacy.

Important Research Considerations

While SS-31 (Elamipretide) demonstrates strong potential in mitochondrial and tissue protection research, it is a potent peptide intended strictly for laboratory use. It has received specific approvals (e.g., Forzinity for Barth syndrome muscle strength) in certain formulations but remains a research chemical in lyophilized vial form for general experimental applications. Common observations include mild injection site reactions (redness, itching, swelling), headache, dizziness, flushing, or transient gastrointestinal discomfort — effects typically mild and resolving quickly. Long-term safety beyond 4–12 weeks is less established; rare considerations include hypersensitivity. Prioritize proper protocols, biomarker monitoring (e.g., ATP levels, ROS markers), and consult qualified professionals for any application beyond strict lab research.

Elevate your mitochondrial and longevity research portfolio with SS-31 (Elamipretide) — where targeted cardiolipin binding meets powerful insights into cellular energy restoration, oxidative stress defense, and tissue vitality. Discover the potential of this advanced mitochondrial-targeted tetrapeptide for groundbreaking studies in aging, performance, and metabolic science.

For research purposes only. Not for human consumption, diagnostic, or therapeutic use. Always comply with local laws and institutional protocols.