kissPeptin

Kisspeptin-10 5mg – Premium Hypothalamic Peptide for Reproductive Hormone Regulation & Fertility Research | Potent GnRH Stimulator to Boost Natural LH, FSH & Testosterone Production Insights

Ignite natural reproductive hormone pathways with Kisspeptin-10 5mg from Ion Peptide, the high-purity synthetic decapeptide designed for advanced laboratory studies on the hypothalamic-pituitary-gonadal (HPG) axis, gonadotropin release, fertility mechanisms, and sexual function. As the bioactive C-terminal fragment of the KISS1 gene product, Kisspeptin-10 acts as a powerful upstream regulator of GnRH neurons, triggering pulsatile secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) — offering researchers a precise, physiologic tool for investigating testosterone production, ovulation support, libido enhancement, and hypogonadism models without direct hormonal supplementation.

Premium Product Overview

Kisspeptin-10 (also known as KP-10 or Metastin 45-54) is supplied as a stable lyophilized acetate salt in convenient 5mg vials for easy reconstitution.

With the sequence Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂, molecular formula C₆₃H₈₃N₁₇O₁₄, and molecular weight of approximately 1302.4 Da, this amidated decapeptide binds with high affinity to the KISS1R (GPR54) receptor on GnRH neurons. Manufactured at ≥99% purity (third-party HPLC & MS verified), Kisspeptin-10 provides researchers with a reliable, potent tool for precise investigations into reproductive endocrinology, puberty onset, and hormone restoration pathways.

Key Research Benefits of Kisspeptin-10

• Potent GnRH & Gonadotropin Stimulation: Rapidly increases LH and FSH secretion in a dose-dependent manner, leading to elevated endogenous testosterone in male models and estrogen/progesterone support in female models.
• Natural Testosterone & Fertility Support: Enhances Leydig cell activity and spermatogenesis while supporting ovulation and menstrual cycle regulation in research settings.
• Libido & Sexual Function Insights: Modulates brain regions involved in sexual arousal and attraction, offering potential for hypoactive sexual desire studies.
• Hypogonadism & Recovery Models: Explored for restoring HPG axis function in conditions involving suppressed gonadotropins, including metabolic stress or post-suppression recovery.
• Synergistic Potential: Frequently studied alongside GnRH analogues or other reproductive peptides for comprehensive fertility and hormone balance research.

Researchers often describe Kisspeptin-10 as the “master upstream regulator” of reproduction — delivering physiologic gonadotropin pulses with high specificity and minimal off-target hormonal disruption.

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Quality Assurance & Usage in Research

Sourced exclusively for laboratory research with USA-verified COAs. Kisspeptin-10 reconstitutes easily with bacteriostatic water. Store lyophilized vials at -20°C and reconstituted solutions refrigerated.

Common Research Protocols (for reference only): Typical subcutaneous or intravenous doses in studied models range from 0.1–3 μg/kg or 100–300 mcg per administration, often as boluses or short infusions. Protocols may explore daily or pulsatile dosing to mimic physiologic GnRH release. Always follow precise reconstitution and institutional guidelines.

Important Research Considerations

Kisspeptin-10 is a potent research chemical intended strictly for laboratory use only. It has shown strong safety in clinical research settings with minimal adverse effects, though mild transient symptoms like flushing, headache, or nausea may occur at higher doses. It is not approved by regulatory agencies for human therapeutic, cosmetic, or performance use. Prioritize proper protocols, biomarker monitoring (LH, FSH, testosterone, estradiol), and consult qualified professionals for any application beyond strict lab research.